Pyridine-2, 6-dicarboxylic acid is an important intermediate in pharmaceutical synthesis and has a wide range of applications. Pyridine-2, 6-dicarboxylic acid occurs naturally in bacterial spores, but the amount is small, cannot meet the demand, and is not easy to extract. It is not conducive to industrial production and application, the earliest synthetic literature reported in 1935, ALVIN.W. Seinger and S.M. McChemicalbookelvain of the University of Wisconsin oxidize 2, 6-dimethylpyridine with potassium permanganate in water as a solvent, the yield is 64%. It is generally prepared by oxidation of 2, 6-dimethylpyridine in industry. Use Pyridine-2, 6-dicarboxylic acid is released from the autoclaving of thermobacterium stearophilus spores. It induces the accumulation of chitosan-stabilized gold nanoparticles, causing the color of the solution to change from red to blue.Pyridine-2, 6-dicarboxylic acid is an important intermediate in pharmaceutical synthesis and has a wide range of applications. Pyridine-2, 6-dicarboxylic acid occurs naturally in bacterial spores, but the amount is small, cannot meet the demand, and is not easy to extract. It is not conducive to industrial production and application, the earliest synthetic literature reported in 1935, ALVIN.W. Seinger and S.M. McElvain of the University of Wisconsin oxidize 2, 6-dimethylpyridine with potassium manganese in the condition of water as solvent, the yield is 64%. It is generally prepared by oxidation of 2, 6-dimethylpyridine in industry.
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